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  1. Several conditions apparent at birth, e.g., neural tube defects (NTDs) and cardiac anomalies, are associated with polymorphisms in folate-related genes, such as the 677C → T polymorphism of the methylenetetrah...

    Authors: Piet Hein Jongbloet, André LM Verbeek, Martin den Heijer and Nel Roeleveld

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2008 5:5

    Content type: Hypothesis

    Published on:

  2. To discuss the meaning of serum oestradiol monitoring in frozen embryo transfer cycle using hormone replacement without pretreatment with gonadotropin hormone (GnRH) agonist.

    Authors: Zhihong Niu, Yun Feng, Yijuan Sun, Aijun Zhang and Huiqin Zhang

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2008 5:4

    Content type: Hypothesis

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  3. Historically, less attention has been paid to paternal effects on early embryogenesis than maternal effects. However, it is now apparent that certain male factor infertility phenotypes are associated with incr...

    Authors: Laszlo Nanassy and Douglas T Carrell

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2008 5:2

    Content type: Review

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  4. In several canine models of hereditary human disease the homozygote dogs die prior to puberty, or have substantially reduced fertility. To create a clinically healthy animal that can be bred, but can also tran...

    Authors: Jennifer K Pullium, Ross Milner and Gary A Tuma

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2008 5:1

    Content type: Short report

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  5. We present a series of monozygous multiple gestations achieved following in vitro fertilization (IVF): one case of monochorionic triplet pregnancy and six cases of dizygotic triplet pregnancy. From September 2...

    Authors: Atsushi Yanaihara, Takeshi Yorimitsu, Hiroshi Motoyama, Hideaki Watanabe and Toshihiro Kawamura

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2007 4:4

    Content type: Case Report

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  6. This research describes current clinical and demographic features sampled from reproductive endocrinology programs currently offering in vitro fertilization (IVF) in the Middle East.

    Authors: Eric Scott Sills, Hussein S Qublan, Zeev Blumenfeld, Ahmad VT Dizaj, Ariel Revel, Serdar Coskun, Imad Abou Jaoude, Gamal Serour, Mamdoh Eskandar, Mohammad Ali Khalili, Aygul Demirol, Krinos Trokoudes, Pelin Ocal, Abdul Munaf Sultan, Benjamin A Lotto and Adele El-Kareh

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2007 4:3

    Content type: Research

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  7. To determine whether estradiol-to-progesterone (E2/P) ratios at the time of embryo transfer (ET) have an effect on implantation and pregnancy in IVF cycles.

    Authors: Irmhild Gruber, Alexander Just, Monika Birner and Alexander Lösch

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2007 4:1

    Content type: Hypothesis

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  8. Intracytoplasmic sperm injection (ICSI) is a component of infertility treatment often employed when conventional in vitro fertilization is unlikely to be successful. Despite good clinical results with ICSI, th...

    Authors: Kevin S Richter, Alana Davis, Jennifer Carter, Stephen J Greenhouse, Gilbert L Mottla and Michael J Tucker

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2006 3:5

    Content type: Research

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  9. Progesterone receptor act as ligand-inducible transcription factor in the respective target cells by binding to specific progesterone response elements in the promoter of the target genes. However, despite the...

    Authors: Shlomit Goldman and Eliezer Shalev

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2006 3:4

    Content type: Hypothesis

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  10. Recent studies have demonstrated that the endogenous cannabinoids are important modulators of fertility in mammals. In particular, a role of the endocannabinoid system in early stages of embryo development, ov...

    Authors: Francesca G Klinger, Natalia Battista, Massimo De Felici and Mauro Maccarrone

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2006 3:3

    Content type: Hypothesis

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  11. Laboratory animals are commonly used for evaluating the physiological properties of the mammalian ovarian follicle and the enclosed oocyte. The use of different species to determine the morphological relations...

    Authors: Jeanine Griffin, Benjamin R Emery, Ivan Huang, C Matthew Peterson and Douglas T Carrell

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2006 3:2

    Content type: Research

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  12. About 30–40% of male infertility is due to unknown reasons. Genetic contributions to the disruption of spermatogenesis are suggested and amongst the genetic factors studied, Y chromosome microdeletions represe...

    Authors: Ali Hellani, Saad Al-Hassan, Muhammed A Iqbal and Serdar Coskun

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2006 3:1

    Content type: Research

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  13. The relation between vascular endothelial growth factor (VEGF) and early luteal function has rarely been proven in humans. The purpose of this study was to define the relation between follicular fluid concentr...

    Authors: F Coppola, B Ferrari, L Barusi, V Caccavari, MC Salvarani and G Piantelli

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2005 2:13

    Content type: Research

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  14. Endometriosis is a complex disease affecting 10–15% of women at reproductive age. Very few genes are known to be altered in this pathology. RIP140 protein is an important cofactor of oestrogen receptor and man...

    Authors: Virginia Caballero, Rocío Ruiz, José Antonio Sainz, Marina Cruz, Miguel Angel López-Nevot, José Jorge Galán, Luis Miguel Real, Francisco de Castro, Vicente López-Villaverde and Agustín Ruiz

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2005 2:11

    Content type: Research

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  15. This overview describes and illustrates the clinical applications of three-dimensional transvaginal sonography in reproductive medicine. Its main applications include assessment of uterine anomalies, intrauter...

    Authors: Nick Raine-Fenning and Arthur C Fleischer

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2005 2:10

    Content type: Commentary

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  16. To compare the frequency of Y-chromosome microdeletions in Japanese and African azoospermic and oligozoospermic men and describe embryo characteristics and reproductive outcome following in vitro fertilization...

    Authors: Paul E Kihaile, Atsushi Yasui and Yoshihiro Shuto

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2005 2:9

    Content type: Research

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  17. The purpose of this study is to determine if low-dose aspirin improved ovarian stimulation, endometrial response, or IVF pregnancy rates in our program.

    Authors: Bradley S Hurst, Jennifer T Bhojwani, Paul B Marshburn, Margaret A Papadakis, Terry A Loeb and Michelle L Matthews

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2005 2:8

    Content type: Research

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  18. Co-culture of embryos with various somatic cells has been suggested as a promising approach to improve embryo development. Despite numerous reports regarding the beneficial effects of epithelial cells from the...

    Authors: Mohamad Reza Baghaban Eslami Nejad, Mojtaba Rezazadeh Valojerdi and Saeed Kazemi Ashtiani

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2005 2:7

    Content type: Research

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  19. The purpose of this study was to localize the expression of steroid sulfatase (STS) in cumulus cells and to determine the relationship between STS mRNA expression and the serum levels of follicle-stimulating h...

    Authors: Yukiko Otsuka, Atsushi Yanaihara, Shinji Iwasaki, Junichi Hasegawa, Takumi Yanaihara and Takashi Okai

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2005 2:6

    Content type: Research

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  20. Some evidence suggests that complementary and alternative medicine (CAM) has found increased utilisation among patients seeking infertility treatment, although there is little information available to quantify...

    Authors: Catherine Coulson and Julian Jenkins

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2005 2:5

    Content type: Short report

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  21. Embryo implantation requires that uterine epithelium develops competence to bind trophoblast to its apical (free) poles. This essential element of uterine receptivity seems to depend on a destabilisation of th...

    Authors: Carola Heneweer, Martina Schmidt, Hans-Werner Denker and Michael Thie

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2005 2:4

    Content type: Research

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  22. The sperm penetration assay (SPA) is used to predict the fertilizing capacity of sperm. Thus, some programs rely on SPA scores to formulate insemination plans in conjunction with in-vitro fertilization (IVF) c...

    Authors: Vincent W Aoki, C Matthew Peterson, Kirtly Parker-Jones, Harry H Hatasaka, Mark Gibson, Ivan Huang and Douglas T Carrell

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2005 2:3

    Content type: Short report

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  23. This article traces the career of Celso-Ramon Garcia (1922–2004), noted physician, educator, and internationally renowned pioneer in the field of reproductive endocrinology. His work helped to formulate oral c...

    Authors: Jerome F Strauss III and Luigi Mastroianni Jr

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2005 2:2

    Content type: Commentary

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  24. Journal of Experimental & Clinical Assisted Reproduction is an Open Access, online, electronic journal published by BioMed Central with full contents available to the scientific and medical community free of c...

    Authors: Eric Scott Sills, Tina Thibault Vincent and Gianpiero D Palermo

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2005 2:1

    Content type: Editorial

    Published on:

  25. Journal of Experimental & Clinical Assisted Reproduction is an open access, online, peer-review journal publishing papers on all aspects of research into reproductive endocrinology, infertility, bioethics and th...

    Authors: E Scott Sills, Robert M Winston and Gianpiero D Palermo

    Citation: Journal of Experimental & Clinical Assisted Reproduction 2004 1:1

    Content type: Editorial

    Published on:

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