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In memoriam: Celso-Ramon Garcia, M.D. (1922–2004), reproductive medicine visionary


This article traces the career of Celso-Ramon Garcia (1922–2004), noted physician, educator, and internationally renowned pioneer in the field of reproductive endocrinology. His work helped to formulate oral contraceptives used by millions of women throughout the world. Garcia's research collaborators included Gregory Pincus and John Rock, who together finalized the landmark clinical data needed to secure initial FDA approval for "the pill" in 1960. In addition to Garcia's monumental work in contraceptive endocrinology, his scholarly interests encompassed physiology of the menopause, minimally invasive reproductive surgery, as well as psychological aspects of infertility. Closely identified with the University of Pennsylvania, Garcia was instrumental in establishing the first formal clinical program in reproductive biology and influenced countless young scientists whose training he supervised and mentored. His distinguished career was emblematic of the best of the medical profession, characterized by compassion, intellect, and a sincere desire to help others. Our manuscript outlines Garcia's wide range of interests, acknowledges his superior fund of knowledge, and honors his humanitarian spirit – all of which contributed to an impressive legacy of medical discoveries. The impact of Prof. Garcia's work will continue to be felt for many years.


  1. Rock J, Pincus G, Garcia C-R: Effects of certain 19-nor steroids on the human menstrual cycle. Science. 1956, 124: 891-893.

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  2. Pincus G, Garcia C-R, Rock J, Paniagua M, Pendleton A, Laraque F, Nicolas R, Borno R, Pean V: Effectiveness of an oral contraceptive; effects of a progestin-estrogen combination upon fertility, menstrual phenomena, and health. Science. 1959, 130: 81-3.

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  3. Pincus G, Garcia C-R, Paniagua M, Shepard J: Ethynodiol diacetate as a new, highly potent oral inhibitor of ovulation. Science. 1962, 138: 439-440.

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  4. Rosenfeld DL, Garcia C-R, Bullock W: An infertility data registry. Fertil Steril. 1978, 29: 112-114.

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  5. Cutler WB, Garcia C-R, Edwards D: Menopause: A guide for women and the men who love them. 1985, W.W. Norton and Company, New York

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Correspondence to Jerome F Strauss III.

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The author(s) declare that they have no competing interests.

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JLS and LM contributed equally to this work and its revisions.

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Open Access This article is published under license to BioMed Central Ltd. This is an Open Access article is distributed under the terms of the Creative Commons Attribution License ( ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Strauss, J.F., Mastroianni, L. In memoriam: Celso-Ramon Garcia, M.D. (1922–2004), reproductive medicine visionary . J Exp Clin Assist Reprod 2, 2 (2005).

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